Another new movie kept "Avatar" from ruling the weekend box office. Since it was Valentine's Day Weekend, it was only right that a new film call "Valentine's Day" took center stage.

The Garry Marshall-directed romance flick easily grabbed the #1 spot over the holiday weekend, taking in $52.4 million to open.

It was a "no-brainer," box office analyst, Paul Dergarabedian told the Associated Press.

It features a star-studded line-up that includes Ashton Kutcher, Jessica Alba, Jennifer Garner, Anne Hathaway, Julia Roberts, Jamie Foxx, Queen Latifah, Jennifer Biel, Shirley MacLaine, Taylor Swift and Taylor Lautner.

"Valentine's Day" is expected to hit the $60 million range after President's Day on Monday (February 15). If it does, it would break the holiday weekend record of $52 million set by "Ghost Rider" over the four-day holiday weekend in 2007.

Opening in a tight race for #2 was the action fantasy "Percy Jackson & the Olympians: The Lightning Thief". earning $31.1 million over three days, and right behind it was the werewolf tale "The Wolfman" with $30.6 million.

"Percy Jackson" was adapted from the opening book in Rick Riordan's fantasy series, and follows the adventures of a teen who learns he's descended from the ancient Greek gods. The cast includes Uma Thurman, Pierce Brosnan, Catherine Keener and Rosario Dawson.

Benicio Del Toro stars in "The Wolfman", alongside Anthony Hopkins and Emily Blunt. It is an update of the 1941 Lon Chaney Jr. horror classic about an aristocrat who returns to his ancestral home and is bitten by a werewolf.

In at #4 was the unstoppable "Avatar", earning another $22 million to raise its domestic total to $659.6 million and its worldwide haul to $2.35 billion.

And to close out the top 5 was the previous weekend's #1 movie, "Dear John," which fell to #5 with $15.3 million.

That wraps things up this weekend. Next weekend, look out for release of the period drama, "Shutter Island," starring Leonardo DiCaprio.

This weekend's top 10 is as follows:

1 - "Valentine's Day," $52.4 million.
2 - "Percy Jackson & the Olympians: The Lightning Thief," $31.1 million.
3 - "The Wolfman," $30.6 million.
4 - "Avatar," $22 million.
5 - "Dear John," $15.3 million.
6 - "The Tooth Fairy," $5.6 million.
7 - "From Paris With Love," $4.7 million.
8 - "Edge of Darkness," $4.6 million.
9 - "Crazy Heart," $4 million.
10 - "When in Rome," $3.4 million.